Can I used XPath selectors in BeautifulSoup?

No, Python's BeautifulSoup doesn't support XPath selectors despite supporting lxml backend which can perform XPath queries.

To use XPath selectors either lxml or parsel packages must be used.

parsel is a modern wrapper around lxml which makes xpath selections very easy:

from parsel import Selector

selector = Selector(text='<div class="price">22.85</div>')
print(selector.xpath("//div[@class='price']/text()").get())
"22.85"

Alternatively, lxml can be used directly:

from lxml import html

tree = html.fromstring('<div class="price">22.85</div>')
print(tree.xpath("//div[@class='price']/text()"))
"22.85"